The guidelines recommend antibiotics for exacerbations in patients with moderate to severe COPD, and evidence shows that they may be effective for those with mild COPD. With increased awareness of the inappropriate use of antibiotics, doctors may have concerns about the emergence of antibiotic resistance as a result of antibiotic use for exacerbations of mild to moderate COPD. Antibiotics are generally reserved for use in episodes of acute exacerbations of chronic bronchitis and emphysema. Theophylline may induce a short-term improvement in FEV1, but the benefits of methylxanthine therapy should be weighed against potential side effects and potential toxicity.
There are several treatment options to control COPD, but sometimes changes to your regimen may be necessary. Despite public education about the dangers of smoking, chronic obstructive pulmonary disease (COPD) remains a major medical problem and is now the fourth leading cause of death in the United States. Smoking cessation in patients with early COPD improves lung function initially and slows the annual decline in FEV1,19—21 Other factors that are positively related to survival include higher partial arterial oxygen pressure (PaO), a history of atopy, and increased ability to dissemination and exercise. Hospitalization of patients with COPD may be necessary to provide antibiotic therapy, adequate supportive care, and monitoring of oxygen status.
A group of researchers43 found significant decreases in hospital admissions and length of hospital stays for acute exacerbations of COPD in patients treated with CPAP and LTOT. A study published in the New England Journal of Medicine found that people with COPD benefited from treatment with the antibiotic azithromycin (Zithromax, Zmax). Short courses of systemic corticosteroids may provide significant benefits in patients with COPD exacerbations. COPD is characterized by degeneration and destruction of the lung and supporting tissue, processes that result in emphysema, chronic bronchitis, or both.
If you have COPD, you are more likely to need and be prescribed antibiotics when you have a respiratory infection, so you should not hesitate to take antibiotics if they are prescribed. Consider taking antibiotics for patients with mild to moderate exacerbations of chronic obstructive pulmonary disease (COPD). Over the years, the practice of using prophylactic antibiotics to prevent exacerbation of COPD has been controversial. During the study, there were 156 COPD hospitalizations for the antibiotic group and 200 for the placebo group.
In fact, the Australian Therapeutic Guidelines, a guide for doctors on how best to treat different diseases, recommend antibiotics to treat respiratory tract infections in people with COPD.